产品描述:Rabbit polyclonal antibody to GLUR2 (Phospho-S880)免疫原:KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S880 of human GLUR2 protein. The exact sequence is proprietary.纯化方式:The antibody was purified by immunogen affinity chromatography.克隆类型:Polyclonal产品形式:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.稀释比:WB (1/500 - 1/1000), IH (1/100 - 1/200)基因名称:GRIA2相关名称:GLUR2; Glutamate receptor 2; GluR-2; AMPA-selective glutamate receptor 2; GluR-B; GluR-K2; Glutamate receptor ionotropic, AMPA 2; GluA2
基因编号(人):
2891;
基因编号(小鼠):
14800;
基因编号(大鼠):
29627;
蛋白编号(人):
P42262;
蛋白编号(小鼠):
P23819;
蛋白编号(大鼠):
P19491;
储存效期:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of GLUR2 (Phospho-S880) expression in mouse muscle (A), rat muscle (B) whole cell lysates. (Predicted band size: 98 kD; Observed band size: 100 kD)
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Immunohistochemical analysis of GLUR2 (Phospho-S880) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
{beta}-Amyloid Impairs AMPA Receptor Trafficking and Function by Reducing Ca2+/Calmodulin-dependent Protein Kinase II Synaptic Distribution
Soluble Oligomers of Amyloid-{beta} Peptide Disrupt Membrane Trafficking of {alpha}-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Contributing to Early Synapse Dysfunction
Diabetes causes transient changes in the composition and phosphorylation of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors and interaction with auxiliary proteins in the rat retina